|
| 论文编号: |
|
| 第一作者所在部门: |
|
| 中文论文题目: |
Visual deprivation selectively reshapes the intrinsic functional architecture of the anterior insula subregions
|
| 英文论文题目: |
Visual deprivation selectively reshapes the intrinsic functional architecture of the anterior insula subregions
|
| 论文题目英文: |
|
| 作者: |
Liu, Lihua
|
| 论文出处: |
|
| 刊物名称: |
SCIENTIFIC REPORTS
|
| 年: |
2017
|
| 卷: |
7 |
| 期: |
|
| 页: |
|
| 联系作者: |
|
| 收录类别: |
|
| 影响因子: |
|
| 摘要: |
The anterior insula (AI) is the core hub of salience network that serves to identify the most relevant stimuli among vast sensory inputs and forward them to higher cognitive regions to guide behaviour. As blind subjects were usually reported with changed perceptive abilities for salient non-visual stimuli, we hypothesized that the resting-state functional network of the AI is selectively reorganized after visual deprivation. The resting-state functional connectivity (FC) of the bilateral dorsal and ventral AI was calculated for twenty congenitally blind (CB), 27 early blind (EB), 44 late blind (LB) individuals and 50 sighted controls (SCs). The FCs of the dorsal AI were strengthened with the dorsal visual stream, while weakened with the ventral visual stream in the blind than the SCs; in contrast, the FCs of the ventral AI of the blind was strengthened with the ventral visual stream. Furthermore, these strengthened FCs of both the dorsal and ventral AI were partially negatively associated with the onset age of blindness. Our result indicates two parallel pathways that selectively transfer non-visual salient information between the deprived "visual" cortex and salience network in blind subjects. |
| 英文摘要: |
|
| 外单位作者单位: |
|
| 备注: |
|
关闭窗口 |
|
