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| 论文编号: |
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| 第一作者所在部门: |
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| 中文论文题目: |
In vivo pentamodal tomographic imaging for small animals
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| 英文论文题目: |
In vivo pentamodal tomographic imaging for small animals
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| 论文题目英文: |
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| 作者: |
Liu, Muhan
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| 论文出处: |
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| 刊物名称: |
BIOMEDICAL OPTICS EXPRESS
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| 年: |
2017
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| 卷: |
8 |
| 期: |
3 |
| 页: |
1356-1371 |
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| 影响因子: |
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| 摘要: |
Multimodality molecular imaging emerges as a powerful strategy for correlating multimodal information. We developed a pentamodal imaging system which can perform positron emission tomography, bioluminescence tomography, fluorescence molecular tomography, Cerenkov luminescence tomography and X-ray computed tomography successively. Performance of sub-systems corresponding to different modalities were characterized. In vivo multimodal imaging of an orthotopic hepatocellular carcinoma xenograft mouse model was performed, and acquired multimodal images were fused. The feasibility of pentamodal tomographic imaging system was successfully validated with the imaging application on the mouse model. The ability of integrating anatomical, metabolic, and pharmacokinetic information promises applications of multimodality molecular imaging in precise medicine. (C) 2017 Optical Society of America. |
| 英文摘要: |
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